ABSTRACT
@#AIM: To observe the morphology of corneal incision between femtosecond laser-assisted cataract surgery(FLACS)with 2.4mm micro-incision and conventional phacoemulsification cataract surgery(CPCS)with 2.4mm micro-incision, evaluating the safety and stability of the incision.<p>METHODS: This was a prospective controlled study. A total of 89 cataract patients(99 eyes)who underwent cataract surgery were collected. All patients were divided into two groups: 44 cases(49 eyes)in FLACS group and 45 cases(50 eyes)in CPCS group. Morphology of clear corneal incision was observed by OCTA postoperative.<p>RESULTS: There was no external wound dehiscence in FLACS group on 1d postoperative, while 10% patients had external wound dehiscence in CPCS group(<i>P</i><0.05). There were no external wound dehiscence in both groups on 1wk, 1mo and 3mo postoperative. On 1wk and 1mo postoperative, the incidences of internal wound dehiscence in FLACS group(47% of 1wk and 10% of 1mo)were lower than that in CPCS group. There were statistically significant difference(68% of 1wk and 26% of 1mo)(<i>P</i><0.05). On 1d and 3mo postoperative, there were no significant difference in internal wound dehiscence in both groups. There were no significant differences in descemet membrane detachment(DMD)in both groups.<p>CONCLUSION: Femtosecond laser-assisted cataract surgery(FLACS)is benefit for wound closure and reducing abnormal incision construction.
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the changes in retinal functions using multifocal electroretinography (mfERG) following intravitreal injection of Lucentis for treatment of wet age-related macular degeneration.</p><p><b>METHODS</b>This prospective study was conducted in 14 patients (9 men and 5 women, 14 eyes) with wet age-related macular degeneration receiving treatment with intravitreal injections of ranibizumab (Lucentis) in our hospital between October, 2014 and January, 2016. All the patients received the treatment following a 1+PRN protocol and after the initial injection, the patients were followed up monthly for 6 months to decide if additional injections were needed. The corrected visual acuity and mfERG findings of the patients were assessed before and at l, 3 and 6 months after the initial injection.</p><p><b>RESULTS</b>At the last follow-up, the patients received injections for a mean of 2.86∓1.58 times. The best corrected visual acuity (BCVA) at 1 month after the initial treatment was not significantly different from that before treatment (P=0.07), but showed significant improvements at 3 and 6 months (P<0.05). In mfERG, the implicit time of the 6 rings showed no significant decrease after the treatment, but the amplitude density of P1 and N1 in rings 1 and 2 improved significantly at 1, 3, and 6 months after the initial injection (P<0.05).</p><p><b>CONCLUSION</b>Multifocal electroretinography can serve as a useful modality for evaluating visual function changes in patients receiving intravitreal injection of Lucentis for wet age-related macular degeneration.</p>